Understanding normal human genital and urethral development is the frst step in unraveling both rare and common congenital penile anomalies, and to draw a proper plan of reconstruction. Despite the high incidence of congenital malformations of the anorectal and urogenital systems in humans, the mechanisms that govern normal anogenital development are still poorly understood.Understanding normal human genital and urethral development is the frst step in unraveling both rare and common congenital penile anomalies, and to draw a proper plan of reconstruction. Despite the high incidence of congenital malformations of the anorectal and urogenital systems in humans, the mechanisms that govern normal anogenital development are still poorly understood.