Antibiotics are secondary metabolites produced by microorganism, which have antimicrobial properties and have been used as a chemotherapeutic agent against infectious and disease causing microbes for decades. The use of antibiotics along with proper sanitation and vaccination has led to drastic decrease in mortality due to infectious diseases that were primarily lethal (Procopio et al. 2012). Isolation of antibiotics from microorganism is much easier than chemical synthesis of these compounds and hence has resulted in discovery of countless novel antibiotics till date (Shlaes 2010). These antibiotics are being used to prevent and cure microbial infections in various spheres of human development such as human medicine, veterinary science, animal husbandry and maintenance of livestock, agriculture, and aquaculture (Kummerer 2009).